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Random Amino Acid Mutations and Protein Misfolding Lead to Shannon Limit in Sequence-Structure Communication

The transmission of genomic information from coding sequence to protein structure during protein synthesis is subject to stochastic errors. To analyze transmission limits in the presence of spurious errors, Shannon's noisy channel theorem is applied to a communication channel between amino acid...

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Detalles Bibliográficos
Autor principal: Lisewski, Andreas Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518838/
https://www.ncbi.nlm.nih.gov/pubmed/18769673
http://dx.doi.org/10.1371/journal.pone.0003110