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Random Amino Acid Mutations and Protein Misfolding Lead to Shannon Limit in Sequence-Structure Communication
The transmission of genomic information from coding sequence to protein structure during protein synthesis is subject to stochastic errors. To analyze transmission limits in the presence of spurious errors, Shannon's noisy channel theorem is applied to a communication channel between amino acid...
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518838/ https://www.ncbi.nlm.nih.gov/pubmed/18769673 http://dx.doi.org/10.1371/journal.pone.0003110 |