Paclitaxel loading in PLGA nanospheres affected the in vitro drug cell accumulation and antiproliferative activity

BACKGROUND: PTX is one of the most widely used drug in oncology due to its high efficacy against solid tumors and several hematological cancers. PTX is administered in a formulation containing 1:1 Cremophor(® )EL (polyethoxylated castor oil) and ethanol, often responsible for toxic effects. Its enca...

Descripción completa

Detalles Bibliográficos
Autores principales: Vicari, Luisa, Musumeci, Teresa, Giannone, Ignazio, Adamo, Luana, Conticello, Concetta, De Maria, Ruggero, Pignatello, Rosario, Puglisi, Giovanni, Gulisano, Massimo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519087/
https://www.ncbi.nlm.nih.gov/pubmed/18657273
http://dx.doi.org/10.1186/1471-2407-8-212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519087/
https://www.ncbi.nlm.nih.gov/pubmed/18657273
http://dx.doi.org/10.1186/1471-2407-8-212

Ejemplares similares