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Paclitaxel loading in PLGA nanospheres affected the in vitro drug cell accumulation and antiproliferative activity

BACKGROUND: PTX is one of the most widely used drug in oncology due to its high efficacy against solid tumors and several hematological cancers. PTX is administered in a formulation containing 1:1 Cremophor(® )EL (polyethoxylated castor oil) and ethanol, often responsible for toxic effects. Its enca...

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Detalles Bibliográficos
Autores principales:	Vicari, Luisa, Musumeci, Teresa, Giannone, Ignazio, Adamo, Luana, Conticello, Concetta, De Maria, Ruggero, Pignatello, Rosario, Puglisi, Giovanni, Gulisano, Massimo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519087/ https://www.ncbi.nlm.nih.gov/pubmed/18657273 http://dx.doi.org/10.1186/1471-2407-8-212

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