Collagen I but not Matrigel matrices provide an MMP-dependent barrier to ovarian cancer cell penetration

BACKGROUND: The invasive potential of cancer cells is usually assessed in vitro using Matrigel as a surrogate basement membrane. Yet cancer cell interaction with collagen I matrices is critical, particularly for the peritoneal metastatic route undertaken by several cancer types including ovarian. Ma...

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Detalles Bibliográficos
Autores principales: Sodek, Katharine L, Brown, Theodore J, Ringuette, Maurice J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519089/
https://www.ncbi.nlm.nih.gov/pubmed/18681958
http://dx.doi.org/10.1186/1471-2407-8-223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519089/
https://www.ncbi.nlm.nih.gov/pubmed/18681958
http://dx.doi.org/10.1186/1471-2407-8-223

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