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Collagen I but not Matrigel matrices provide an MMP-dependent barrier to ovarian cancer cell penetration
BACKGROUND: The invasive potential of cancer cells is usually assessed in vitro using Matrigel as a surrogate basement membrane. Yet cancer cell interaction with collagen I matrices is critical, particularly for the peritoneal metastatic route undertaken by several cancer types including ovarian. Ma...
Autores principales: | Sodek, Katharine L, Brown, Theodore J, Ringuette, Maurice J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519089/ https://www.ncbi.nlm.nih.gov/pubmed/18681958 http://dx.doi.org/10.1186/1471-2407-8-223 |
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