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Contemporary approaches for modifying the mouse genome
The mouse is a premiere experimental organism that has contributed significantly to our understanding of vertebrate biology. Manipulation of the mouse genome via embryonic stem (ES) cell technology makes it possible to engineer an almost limitless repertoire of mutations to model human disease and a...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Physiological Society
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519963/ https://www.ncbi.nlm.nih.gov/pubmed/18559964 http://dx.doi.org/10.1152/physiolgenomics.90242.2008 |