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Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

Virus-infected cells secrete a broad range of interferon (IFN) subtypes which in turn trigger the synthesis of antiviral factors that confer host resistance. IFN-α, IFN-β and other type I IFNs signal through a common universally expressed cell surface receptor, whereas IFN-λ uses a distinct receptor...

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Detalles Bibliográficos
Autores principales: Mordstein, Markus, Kochs, Georg, Dumoutier, Laure, Renauld, Jean-Christophe, Paludan, Søren R., Klucher, Kevin, Staeheli, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2522277/
https://www.ncbi.nlm.nih.gov/pubmed/18787692
http://dx.doi.org/10.1371/journal.ppat.1000151