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Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses
Virus-infected cells secrete a broad range of interferon (IFN) subtypes which in turn trigger the synthesis of antiviral factors that confer host resistance. IFN-α, IFN-β and other type I IFNs signal through a common universally expressed cell surface receptor, whereas IFN-λ uses a distinct receptor...
Autores principales: | Mordstein, Markus, Kochs, Georg, Dumoutier, Laure, Renauld, Jean-Christophe, Paludan, Søren R., Klucher, Kevin, Staeheli, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2522277/ https://www.ncbi.nlm.nih.gov/pubmed/18787692 http://dx.doi.org/10.1371/journal.ppat.1000151 |
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