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Receptor-Associated Protein (RAP) Plays a Central Role in Modulating Aβ Deposition in APP/PS1 Transgenic Mice

BACKGROUND: Receptor associated protein (RAP) functions in the endoplasmic reticulum (ER) to assist in the maturation of several membrane receptor proteins, including low density lipoprotein receptor-related protein (LRP) and lipoprotein receptor 11 (SorLA/LR11). Previous studies in cell and mouse m...

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Detalles Bibliográficos
Autores principales: Xu, Guilian, Karch, Celeste, Li, Ning, Lin, Nianwei, Fromholt, David, Gonzales, Victoria, Borchelt, David R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2522286/
https://www.ncbi.nlm.nih.gov/pubmed/18776935
http://dx.doi.org/10.1371/journal.pone.0003159