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Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin

Kinetochores bind microtubules laterally in a transient fashion and stably, by insertion of plus ends. These pathways may exist to carry out distinct tasks during different stages of mitosis and likely depend on distinct molecular mechanisms. On isolated chromosomes, we found microtubule nucleation/...

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Detalles Bibliográficos
Autores principales: Vorozhko, Valeriya V., Emanuele, Michael J., Kallio, Marko J., Stukenberg, P. Todd, Gorbsky, Gary J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2522317/
https://www.ncbi.nlm.nih.gov/pubmed/18057949
http://dx.doi.org/10.1007/s00412-007-0135-3