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A-Kinase Anchoring Protein Targeting of Protein Kinase A and Regulation of HERG Channels

Adrenergic stimulation of the heart initiates a signaling cascade in cardiac myocytes that increases the concentration of cAMP. Although cAMP elevation may occur over a large area of a target-organ cell, its effects are often more restricted due to local concentration of its main effector, protein k...

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Detalles Bibliográficos
Autores principales: Li, Yan, Sroubek, Jakub, Krishnan, Yamini, McDonald, Thomas V.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2522378/
https://www.ncbi.nlm.nih.gov/pubmed/18679741
http://dx.doi.org/10.1007/s00232-008-9118-4