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A-Kinase Anchoring Protein Targeting of Protein Kinase A and Regulation of HERG Channels
Adrenergic stimulation of the heart initiates a signaling cascade in cardiac myocytes that increases the concentration of cAMP. Although cAMP elevation may occur over a large area of a target-organ cell, its effects are often more restricted due to local concentration of its main effector, protein k...
Autores principales: | Li, Yan, Sroubek, Jakub, Krishnan, Yamini, McDonald, Thomas V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2522378/ https://www.ncbi.nlm.nih.gov/pubmed/18679741 http://dx.doi.org/10.1007/s00232-008-9118-4 |
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