Distinct Methylation of the Interferon γ (IFN-γ) and Interleukin 3 (IL-3) Genes in Newly Activated Primary CD8(+) T Lymphocytes: Regional IFN-γ Promoter Demethylation and mRNA Expression Are Heritable in CD44(high)CD8(+) T Cells

Differential genomic DNA methylation has the potential to influence the development of T cell cytokine production profiles. Therefore, we have conducted a clonal analysis of interferon (IFN)-γ and interleukin (IL)-3 gene methylation and messenger (m)RNA expression in primary CD8(+) T cells during th...

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Detalles Bibliográficos
Autores principales: Fitzpatrick, David R., Shirley, Kym M., McDonald, Louise E., Bielefeldt-Ohmann, Helle, Kay, Graham F., Kelso, Anne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525536/
https://www.ncbi.nlm.nih.gov/pubmed/9653088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525536/
https://www.ncbi.nlm.nih.gov/pubmed/9653088

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