B Lymphocytes Producing Demyelinating Autoantibodies: Development and Function in Gene-targeted Transgenic Mice

We studied the cellular basis of self tolerance of B cells specific for brain autoantigens using transgenic mice engineered to produce high titers of autoantibodies against the myelin oligodendrocyte glycoprotein (MOG), a surface component of central nervous system myelin. We generated “knock-in” mi...

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Detalles Bibliográficos
Autores principales: Litzenburger, Tobias, Fässler, Reinhard, Bauer, Jan, Lassmann, Hans, Linington, Christopher, Wekerle, Hartmut, Iglesias, Antonio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525547/
https://www.ncbi.nlm.nih.gov/pubmed/9653093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525547/
https://www.ncbi.nlm.nih.gov/pubmed/9653093

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