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B Lymphocytes Producing Demyelinating Autoantibodies: Development and Function in Gene-targeted Transgenic Mice
We studied the cellular basis of self tolerance of B cells specific for brain autoantigens using transgenic mice engineered to produce high titers of autoantibodies against the myelin oligodendrocyte glycoprotein (MOG), a surface component of central nervous system myelin. We generated “knock-in” mi...
Autores principales: | Litzenburger, Tobias, Fässler, Reinhard, Bauer, Jan, Lassmann, Hans, Linington, Christopher, Wekerle, Hartmut, Iglesias, Antonio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525547/ https://www.ncbi.nlm.nih.gov/pubmed/9653093 |
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