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PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse
Imprinted genes are important in development and their allelic expression is mediated by imprinting control regions (ICRs). On their DNA-methylated allele, ICRs are marked by trimethylation at H3 Lys 9 (H3K9me3) and H4 Lys 20 (H4K20me3), similar to pericentric heterochromatin. Here, we investigate w...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525564/ https://www.ncbi.nlm.nih.gov/pubmed/18724273 http://dx.doi.org/10.1038/embor.2008.147 |