PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse

Imprinted genes are important in development and their allelic expression is mediated by imprinting control regions (ICRs). On their DNA-methylated allele, ICRs are marked by trimethylation at H3 Lys 9 (H3K9me3) and H4 Lys 20 (H4K20me3), similar to pericentric heterochromatin. Here, we investigate w...

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Detalles Bibliográficos
Autores principales: Pannetier, Maëlle, Julien, Eric, Schotta, Gunnar, Tardat, Mathieu, Sardet, Claude, Jenuwein, Thomas, Feil, Robert
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Scientific Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525564/
https://www.ncbi.nlm.nih.gov/pubmed/18724273
http://dx.doi.org/10.1038/embor.2008.147

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