EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-γ and IL-2

Symptomatic primary Epstein-Barr virus (EBV) infection and elevated humoral immune responses to EBV are associated with an increased risk of developing multiple sclerosis (MS). We explored mechanisms leading to this change in EBV-specific immunity in untreated patients with MS and healthy virus carr...

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Detalles Bibliográficos
Autores principales: Lünemann, Jan D., Jelčić, Ilijas, Roberts, Susanne, Lutterotti, Andreas, Tackenberg, Björn, Martin, Roland, Münz, Christian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525578/
https://www.ncbi.nlm.nih.gov/pubmed/18663124
http://dx.doi.org/10.1084/jem.20072397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525578/
https://www.ncbi.nlm.nih.gov/pubmed/18663124
http://dx.doi.org/10.1084/jem.20072397

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