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Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1–dependent leukocyte recruitment in vivo

Thrombin, acting through a family of protease-activated receptors (PARs), is known to amplify inflammatory responses, but the in vivo importance of PARs in inflammation is not fully appreciated. In a mouse heart-to-rat transplant model, where it is possible to distinguish graft (mouse) from systemic...

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Detalles Bibliográficos
Autores principales: Chen, Daxin, Carpenter, Adam, Abrahams, Joel, Chambers, Rachel C., Lechler, Robert I., McVey, John H., Dorling, Anthony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525584/
https://www.ncbi.nlm.nih.gov/pubmed/18606855
http://dx.doi.org/10.1084/jem.20071427