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Tolerance of NK cells encountering their viral ligand during development

During development, T and B cells encountering their cognate ligands via antigen-specific receptors are deleted or rendered anergic. Like T and B cells, natural killer (NK) cells express certain receptors, such as Ly49H, associated with immunoreceptor tyrosine-based activation motif–bearing adaptor...

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Detalles Bibliográficos
Autores principales: Sun, Joseph C., Lanier, Lewis L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525590/
https://www.ncbi.nlm.nih.gov/pubmed/18606858
http://dx.doi.org/10.1084/jem.20072448