Avidity maturation of memory CD8 T cells is limited by self-antigen expression

Immune tolerance to self-antigens is a complex process that utilizes multiple mechanisms working in concert to maintain homeostasis and prevent autoimmunity. We developed a system that revealed a population of self-specific CD8 T cells within the endogenous T cell repertoire. Immunization of ovalbum...

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Detalles Bibliográficos
Autores principales: Turner, Michael J., Jellison, Evan R., Lingenheld, Elizabeth G., Puddington, Lynn, Lefrançois, Leo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525599/
https://www.ncbi.nlm.nih.gov/pubmed/18625745
http://dx.doi.org/10.1084/jem.20072390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525599/
https://www.ncbi.nlm.nih.gov/pubmed/18625745
http://dx.doi.org/10.1084/jem.20072390

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