Cargando…

Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo

Src homology 2 domain–containing leukocyte phosphoprotein of 76 kD (SLP76), an adaptor that plays a critical role in platelet activation in vitro, contains three N-terminal tyrosine residues that are essential for its function. We demonstrate that mice containing complementary tyrosine to phenylalan...

Descripción completa

Detalles Bibliográficos
Autores principales: Bezman, Natalie A., Lian, Lurong, Abrams, Charles S., Brass, Lawrence F., Kahn, Mark L., Jordan, Martha S., Koretzky, Gary A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525600/
https://www.ncbi.nlm.nih.gov/pubmed/18663126
http://dx.doi.org/10.1084/jem.20080240