Cargando…

Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line

BACKGROUND: In prostate cancer, the identification of drug combinations that could reduce the tumor cell population and rapidly eradicate hormone-resistant cells potentially present would be a remarkable breakthrough in the treatment of this disease. METHODS: The study was performed on a hormone-sen...

Descripción completa

Detalles Bibliográficos
Autores principales: Fabbri, Francesco, Brigliadori, Giovanni, Carloni, Silvia, Ulivi, Paola, Vannini, Ivan, Tesei, Anna, Silvestrini, Rosella, Amadori, Dino, Zoli, Wainer
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525627/
https://www.ncbi.nlm.nih.gov/pubmed/18691406
http://dx.doi.org/10.1186/1479-5876-6-43