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Desensitization of Mouse Nicotinic Acetylcholine Receptor Channels : A Two-Gate Mechanism

The rate constants of acetylcholine receptor channels (AChR) desensitization and recovery were estimated from the durations and frequencies of clusters of single-channel currents. Diliganded-open AChR desensitize much faster than either unliganded- or diliganded-closed AChR, which indicates that the...

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Detalles Bibliográficos
Autores principales: Auerbach, Anthony, Akk, Gustav
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525745/
https://www.ncbi.nlm.nih.gov/pubmed/9689026