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A Mutation in S6 of Shaker Potassium Channels Decreases the K(+) Affinity of an Ion Binding Site Revealing Ion–Ion Interactions in the Pore

Under physiological conditions, potassium channels are extraordinarily selective for potassium over other ions. However, in the absence of potassium, certain potassium channels can conduct sodium. Sodium flux is blocked by the addition of low concentrations of potassium. Potassium affinity, and ther...

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Detalles Bibliográficos
Autores principales: Ogielska, Eva M., Aldrich, Richard W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525752/
https://www.ncbi.nlm.nih.gov/pubmed/9689030