Cargando…

A Random shRNA-Encoding Library for Phenotypic Selection and Hit-Optimization

RNA interference (RNAi) is a mechanism for inhibiting gene expression through the action of small, non-coding RNAs. Most existing RNAi libraries target single genes through canonical pathways. Endogenous microRNAs (miRNAs), however, often target multiple genes and can act through non-canonical pathw...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yongping, Wang, Yun E., Cotticelli, M. Grazia, Wilson, Robert B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525836/
https://www.ncbi.nlm.nih.gov/pubmed/18779859
http://dx.doi.org/10.1371/journal.pone.0003171