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A Random shRNA-Encoding Library for Phenotypic Selection and Hit-Optimization
RNA interference (RNAi) is a mechanism for inhibiting gene expression through the action of small, non-coding RNAs. Most existing RNAi libraries target single genes through canonical pathways. Endogenous microRNAs (miRNAs), however, often target multiple genes and can act through non-canonical pathw...
Autores principales: | Wang, Yongping, Wang, Yun E., Cotticelli, M. Grazia, Wilson, Robert B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525836/ https://www.ncbi.nlm.nih.gov/pubmed/18779859 http://dx.doi.org/10.1371/journal.pone.0003171 |
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