Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways

The yeast URA2 gene, encoding the rate-limiting enzyme of UTP biosynthesis, is transcriptionally activated by UTP shortage. In contrast to other genes of the UTP pathway, this activation is not governed by the Ppr1 activator. Moreover, it is not due to an increased recruitment of RNA polymerase II a...

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Detalles Bibliográficos
Autores principales: Kwapisz, Marta, Wery, Maxime, Després, Daphné, Ghavi-Helm, Yad, Soutourina, Julie, Thuriaux, Pierre, Lacroute, François
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525842/
https://www.ncbi.nlm.nih.gov/pubmed/18716630
http://dx.doi.org/10.1038/emboj.2008.165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525842/
https://www.ncbi.nlm.nih.gov/pubmed/18716630
http://dx.doi.org/10.1038/emboj.2008.165

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