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Genome-wide screens for effective siRNAs through assessing the size of siRNA effects

BACKGROUND: RNA interference (RNAi) has been seen as a revolution in functional genomics and system biology. Genome-wide RNAi research relies on the development of RNAi high-throughput screening (HTS) assays. One of the most fundamental challenges in RNAi HTS is to glean biological significance from...

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Detalles Bibliográficos
Autor principal: Zhang, Xiaohua Douglas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526086/
https://www.ncbi.nlm.nih.gov/pubmed/18710486
http://dx.doi.org/10.1186/1756-0500-1-33