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Metabolic Dynamics in Skeletal Muscle during Acute Reduction in Blood Flow and Oxygen Supply to Mitochondria: In-Silico Studies Using a Multi-Scale, Top-Down Integrated Model

Control mechanisms of cellular metabolism and energetics in skeletal muscle that may become evident in response to physiological stresses such as reduction in blood flow and oxygen supply to mitochondria can be quantitatively understood using a multi-scale computational model. The analysis of dynami...

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Detalles Bibliográficos
Autores principales: Dash, Ranjan K., Li, Yanjun, Kim, Jaeyeon, Beard, Daniel A., Saidel, Gerald M., Cabrera, Marco E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526172/
https://www.ncbi.nlm.nih.gov/pubmed/18779864
http://dx.doi.org/10.1371/journal.pone.0003168