Human MLH1 Protein Participates in Genomic Damage Checkpoint Signaling in Response to DNA Interstrand Crosslinks, while MSH2 Functions in DNA Repair

DNA interstrand crosslinks (ICLs) are among the most toxic types of damage to a cell. For this reason, many ICL-inducing agents are effective therapeutic agents. For example, cisplatin and nitrogen mustards are used for treating cancer and psoralen plus UVA (PUVA) is useful for treating psoriasis. H...

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Detalles Bibliográficos
Autores principales: Wu, Qi, Vasquez, Karen M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526179/
https://www.ncbi.nlm.nih.gov/pubmed/18787700
http://dx.doi.org/10.1371/journal.pgen.1000189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526179/
https://www.ncbi.nlm.nih.gov/pubmed/18787700
http://dx.doi.org/10.1371/journal.pgen.1000189

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