Repertoire-based selection into the marginal zone compartment during B cell development

Marginal zone (MZ) B cells resemble fetally derived B1 B cells in their innate-like rapid responses to bacterial pathogens, but the basis for this is unknown. We report that the MZ is enriched in “fetal-type” B cell receptors lacking N regions (N(−)). Mixed bone marrow (BM) chimeras, made with adult...

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Detalles Bibliográficos
Autores principales: Carey, John B., Moffatt-Blue, Chantelle S., Watson, Lisa C., Gavin, Amanda L., Feeney, Ann J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526199/
https://www.ncbi.nlm.nih.gov/pubmed/18710933
http://dx.doi.org/10.1084/jem.20080559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526199/
https://www.ncbi.nlm.nih.gov/pubmed/18710933
http://dx.doi.org/10.1084/jem.20080559

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