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Repertoire-based selection into the marginal zone compartment during B cell development
Marginal zone (MZ) B cells resemble fetally derived B1 B cells in their innate-like rapid responses to bacterial pathogens, but the basis for this is unknown. We report that the MZ is enriched in “fetal-type” B cell receptors lacking N regions (N(−)). Mixed bone marrow (BM) chimeras, made with adult...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526199/ https://www.ncbi.nlm.nih.gov/pubmed/18710933 http://dx.doi.org/10.1084/jem.20080559 |