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ADAMTS13: a new link between thrombosis and inflammation

von Willebrand factor (VWF) levels are elevated and a disintegrin-like and metalloprotease with thrombospondin type I repeats–13 (ADAMTS13) activity is decreased in both acute and chronic inflammation. We hypothesized that by cleaving hyperactive ultralarge VWF (ULVWF) multimers, ADAMTS13 down-regul...

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Detalles Bibliográficos
Autores principales: Chauhan, Anil K., Kisucka, Janka, Brill, Alexander, Walsh, Meghan T., Scheiflinger, Friedrich, Wagner, Denisa D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526201/
https://www.ncbi.nlm.nih.gov/pubmed/18695007
http://dx.doi.org/10.1084/jem.20080130