Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation

Biological functions of proteins are influenced by posttranslational modifications such as on/off switching by phosphorylation and modulation by glycosylation. Proteolytic processing regulates cytokine and chemokine activities. In this study, we report that natural posttranslational citrullination o...

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Detalles Bibliográficos
Autores principales: Proost, Paul, Loos, Tamara, Mortier, Anneleen, Schutyser, Evemie, Gouwy, Mieke, Noppen, Samuel, Dillen, Chris, Ronsse, Isabelle, Conings, René, Struyf, Sofie, Opdenakker, Ghislain, Maudgal, Prabhat C., Van Damme, Jo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526203/
https://www.ncbi.nlm.nih.gov/pubmed/18710930
http://dx.doi.org/10.1084/jem.20080305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526203/
https://www.ncbi.nlm.nih.gov/pubmed/18710930
http://dx.doi.org/10.1084/jem.20080305

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