Cargando…

Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation

Biological functions of proteins are influenced by posttranslational modifications such as on/off switching by phosphorylation and modulation by glycosylation. Proteolytic processing regulates cytokine and chemokine activities. In this study, we report that natural posttranslational citrullination o...

Descripción completa

Detalles Bibliográficos
Autores principales: Proost, Paul, Loos, Tamara, Mortier, Anneleen, Schutyser, Evemie, Gouwy, Mieke, Noppen, Samuel, Dillen, Chris, Ronsse, Isabelle, Conings, René, Struyf, Sofie, Opdenakker, Ghislain, Maudgal, Prabhat C., Van Damme, Jo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526203/
https://www.ncbi.nlm.nih.gov/pubmed/18710930
http://dx.doi.org/10.1084/jem.20080305

Ejemplares similares