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Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation
Biological functions of proteins are influenced by posttranslational modifications such as on/off switching by phosphorylation and modulation by glycosylation. Proteolytic processing regulates cytokine and chemokine activities. In this study, we report that natural posttranslational citrullination o...
Autores principales: | Proost, Paul, Loos, Tamara, Mortier, Anneleen, Schutyser, Evemie, Gouwy, Mieke, Noppen, Samuel, Dillen, Chris, Ronsse, Isabelle, Conings, René, Struyf, Sofie, Opdenakker, Ghislain, Maudgal, Prabhat C., Van Damme, Jo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526203/ https://www.ncbi.nlm.nih.gov/pubmed/18710930 http://dx.doi.org/10.1084/jem.20080305 |
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