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Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity

Allergic contact hypersensitivity (CHS) is a T cell–mediated inflammatory skin disease. Interleukin (IL)-12 is considered to be important in the generation of the allergen-specific T cell response. Loss of IL-12 function in IL-12Rβ2–deficient mice, however, did not ameliorate the allergic immune res...

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Detalles Bibliográficos
Autores principales: Martin, Stefan F., Dudda, Jan C., Bachtanian, Eva, Lembo, Annalisa, Liller, Stefanie, Dürr, Christoph, Heimesaat, Markus M., Bereswill, Stefan, Fejer, György, Vassileva, Ralitsa, Jakob, Thilo, Freudenberg, Nikolaus, Termeer, Christian C., Johner, Caroline, Galanos, Chris, Freudenberg, Marina A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526208/
https://www.ncbi.nlm.nih.gov/pubmed/18725520
http://dx.doi.org/10.1084/jem.20070509