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Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity
Allergic contact hypersensitivity (CHS) is a T cell–mediated inflammatory skin disease. Interleukin (IL)-12 is considered to be important in the generation of the allergen-specific T cell response. Loss of IL-12 function in IL-12Rβ2–deficient mice, however, did not ameliorate the allergic immune res...
Autores principales: | Martin, Stefan F., Dudda, Jan C., Bachtanian, Eva, Lembo, Annalisa, Liller, Stefanie, Dürr, Christoph, Heimesaat, Markus M., Bereswill, Stefan, Fejer, György, Vassileva, Ralitsa, Jakob, Thilo, Freudenberg, Nikolaus, Termeer, Christian C., Johner, Caroline, Galanos, Chris, Freudenberg, Marina A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526208/ https://www.ncbi.nlm.nih.gov/pubmed/18725520 http://dx.doi.org/10.1084/jem.20070509 |
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