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Electrophysiological and arrhythmogenic effects of 5-hydroxytryptamine on human atrial cells are reduced in atrial fibrillation

5-Hydroxytryptamine (5-HT) is proarrhythmic in atrial cells from patients in sinus rhythm (SR) via activation of 5-HT(4) receptors, but its effects in atrial cells from patients with atrial fibrillation (AF) are unknown. The whole-cell perforated patch-clamp technique was used to record L-type Ca(2+...

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Detalles Bibliográficos
Autores principales: Pau, Davide, Workman, Antony J., Kane, Kathleen A., Rankin, Andrew C.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526346/
https://www.ncbi.nlm.nih.gov/pubmed/16989857
http://dx.doi.org/10.1016/j.yjmcc.2006.08.007