Identification of restriction endonuclease with potential ability to cleave the HSV-2 genome: Inherent potential for biosynthetic versus live recombinant microbicides

BACKGROUND: Herpes Simplex virus types 1 and 2 are enveloped viruses with a linear dsDNA genome of ~120–200 kb. Genital infection with HSV-2 has been denoted as a major risk factor for acquisition and transmission of HIV-1. Developing biomedical strategies for HSV-2 prevention is thus a central stra...

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Detalles Bibliográficos
Autores principales: Wayengera, Misaki, Kajumbula, Henry, Byarugaba, Wilson
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526989/
https://www.ncbi.nlm.nih.gov/pubmed/18687114
http://dx.doi.org/10.1186/1742-4682-5-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526989/
https://www.ncbi.nlm.nih.gov/pubmed/18687114
http://dx.doi.org/10.1186/1742-4682-5-18

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