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GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos

BACKGROUND: GATA factors 4/5/6 have been implicated in the development of the heart and endodermal derivatives in vertebrates. Work in zebrafish has indicated that GATA5 is required for normal development earlier than GATA4/6. However, the GATA5 knockout mouse has no apparent embryonic phenotype, th...

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Detalles Bibliográficos
Autores principales: Haworth, Kim E, Kotecha, Surendra, Mohun, Timothy J, Latinkic, Branko V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526999/
https://www.ncbi.nlm.nih.gov/pubmed/18662378
http://dx.doi.org/10.1186/1471-213X-8-74