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Human BLyS Facilitates Engraftment of Human PBL Derived B Cells in Immunodeficient Mice

The production of fully immunologically competent humanized mice engrafted with peripheral lymphocyte populations provides a model for in vivo testing of new vaccines, the durability of immunological memory and cancer therapies. This approach is limited, however, by the failure to efficiently engraf...

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Detalles Bibliográficos
Autores principales: Schmidt, Madelyn R., Appel, Michael C., Giassi, Lisa J., Greiner, Dale L., Shultz, Leonard D., Woodland, Robert T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527131/
https://www.ncbi.nlm.nih.gov/pubmed/18784835
http://dx.doi.org/10.1371/journal.pone.0003192