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Human BLyS Facilitates Engraftment of Human PBL Derived B Cells in Immunodeficient Mice
The production of fully immunologically competent humanized mice engrafted with peripheral lymphocyte populations provides a model for in vivo testing of new vaccines, the durability of immunological memory and cancer therapies. This approach is limited, however, by the failure to efficiently engraf...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527131/ https://www.ncbi.nlm.nih.gov/pubmed/18784835 http://dx.doi.org/10.1371/journal.pone.0003192 |