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CD11c+ antigen presenting cells from the alveolar space, lung parenchyma and spleen differ in their phenotype and capabilities to activate naïve and antigen-primed T cells

BACKGROUND: The lung is divided into two major compartments: the alveolar space and the parenchyma. The alveolar macrophages are the first line of leukocytes in the lung taking up incoming microbes or microbial antigens whereas the parenchymal dendritic cells (DCs) are believed to be the sole potent...

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Detalles Bibliográficos
Autores principales: Kugathasan, Kapilan, Roediger, Elizabeth K, Small, Cherrie-Lee, McCormick, Sarah, Yang, Pingchang, Xing, Zhou
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527294/
https://www.ncbi.nlm.nih.gov/pubmed/18700962
http://dx.doi.org/10.1186/1471-2172-9-48