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Biomarkers for ragwort poisoning in horses: identification of protein targets

BACKGROUND: Ingestion of the poisonous weed ragwort (Senecio jacobea) by horses leads to irreversible liver damage. The principal toxins of ragwort are the pyrrolizidine alkaloids that are rapidly metabolised to highly reactive and cytotoxic pyrroles, which can escape into the circulation and bind t...

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Detalles Bibliográficos
Autores principales: Moore, Rowan E, Knottenbelt, Derek, Matthews, Jacqueline B, Beynon, Robert J, Whitfield, Phillip D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527303/
https://www.ncbi.nlm.nih.gov/pubmed/18691403
http://dx.doi.org/10.1186/1746-6148-4-30