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Genome wide SNP comparative analysis between EGFR and KRAS mutated NSCLC and characterization of two models of oncogenic cooperation in non-small cell lung carcinoma

BACKGROUND: Lung cancer with EGFR mutation was shown to be a specific clinical entity. In order to better understand the biology behind this disease we used a genome wide characterization of loss of heterozygosity and amplification by Single Nucleotide Polymorphism (SNP) Array analysis to point out...

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Detalles Bibliográficos
Autores principales: Blons, Hélène, Pallier, Karine, Le Corre, Delphine, Danel, Claire, Tremblay-Gravel, Maxime, Houdayer, Claude, Fabre-Guillevin, Elizabeth, Riquet, Marc, Dessen, Philippe, Laurent-Puig, Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527324/
https://www.ncbi.nlm.nih.gov/pubmed/18549475
http://dx.doi.org/10.1186/1755-8794-1-25