Natural Selection Fails to Optimize Mutation Rates for Long-Term Adaptation on Rugged Fitness Landscapes

The rate of mutation is central to evolution. Mutations are required for adaptation, yet most mutations with phenotypic effects are deleterious. As a consequence, the mutation rate that maximizes adaptation will be some intermediate value. Here, we used digital organisms to investigate the ability o...

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Detalles Bibliográficos
Autores principales: Clune, Jeff, Misevic, Dusan, Ofria, Charles, Lenski, Richard E., Elena, Santiago F., Sanjuán, Rafael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527516/
https://www.ncbi.nlm.nih.gov/pubmed/18818724
http://dx.doi.org/10.1371/journal.pcbi.1000187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527516/
https://www.ncbi.nlm.nih.gov/pubmed/18818724
http://dx.doi.org/10.1371/journal.pcbi.1000187

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