Multiple Advantageous Amino Acid Variants in the NAT2 Gene in Human Populations

BACKGROUND: Genetic variation at NAT2 has been long recognized as the cause of differential ability to metabolize a wide variety of drugs of therapeutic use. Here, we explore the pattern of genetic variation in 12 human populations that significantly extend the geographic range and resolution of pre...

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Detalles Bibliográficos
Autores principales: Luca, Francesca, Bubba, Giuseppina, Basile, Massimo, Brdicka, Radim, Michalodimitrakis, Emmanuel, Rickards, Olga, Vershubsky, Galina, Quintana-Murci, Lluis, Kozlov, Andrey I., Novelletto, Andrea
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527519/
https://www.ncbi.nlm.nih.gov/pubmed/18773084
http://dx.doi.org/10.1371/journal.pone.0003136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527519/
https://www.ncbi.nlm.nih.gov/pubmed/18773084
http://dx.doi.org/10.1371/journal.pone.0003136

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