Cargando…
Multiple Advantageous Amino Acid Variants in the NAT2 Gene in Human Populations
BACKGROUND: Genetic variation at NAT2 has been long recognized as the cause of differential ability to metabolize a wide variety of drugs of therapeutic use. Here, we explore the pattern of genetic variation in 12 human populations that significantly extend the geographic range and resolution of pre...
Autores principales: | Luca, Francesca, Bubba, Giuseppina, Basile, Massimo, Brdicka, Radim, Michalodimitrakis, Emmanuel, Rickards, Olga, Vershubsky, Galina, Quintana-Murci, Lluis, Kozlov, Andrey I., Novelletto, Andrea |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527519/ https://www.ncbi.nlm.nih.gov/pubmed/18773084 http://dx.doi.org/10.1371/journal.pone.0003136 |
Ejemplares similares
-
Spatially Explicit Models to Investigate Geographic Patterns in the Distribution of Forensic STRs: Application to the North-Eastern Mediterranean
por: Messina, Francesco, et al.
Publicado: (2016) -
Vitamin D status of northern indigenous people of Russia leading traditional and “modernized” way of life
por: Kozlov, Andrew, et al.
Publicado: (2014) -
Human genome variability and host-pathogen interactions
por: Quintana-Murci, Lluis
Publicado: (2009) -
Understanding rare and common diseases in the context of human evolution
por: Quintana-Murci, Lluis
Publicado: (2016) -
Evolutionary genetics as a tool to target genes involved in phenotypes of medical relevance
por: Heyer, Evelyne, et al.
Publicado: (2009)