MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult

BACKGROUND: An endotoxin insult mimics a severe peripheral infection and recent evidence suggests that a single exposure can cause long-term cognitive deficits. A peripheral injection of LPS results in production of pro-inflammatory cytokines, such as IL-1β and TNF-α, in the brain and periphery and...

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Detalles Bibliográficos
Autores principales: Thompson, Wendy L, Karpus, William J, Van Eldik, Linda J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527558/
https://www.ncbi.nlm.nih.gov/pubmed/18706086
http://dx.doi.org/10.1186/1742-2094-5-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527558/
https://www.ncbi.nlm.nih.gov/pubmed/18706086
http://dx.doi.org/10.1186/1742-2094-5-35

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