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Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice

BACKGROUND: Several transgenic animal models genetically predisposed to develop Alzheimer's disease (AD)-like pathology have been engineered to facilitate the study of disease pathophysiology and the vetting of potential disease-modifying therapeutics. The triple transgenic mouse model of AD (3...

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Detalles Bibliográficos
Autores principales: Mastrangelo, Michael A, Bowers, William J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527610/
https://www.ncbi.nlm.nih.gov/pubmed/18700006
http://dx.doi.org/10.1186/1471-2202-9-81